Niacinamide (Vitamin B3) helps balance oil, reduce redness, and reinforce the skin barrier for smoother, calmer-looking skin.
Niacinamide is a multitasking active that supports healthier-looking pores, a stronger barrier, and a more even tone. It helps regulate excess sebum, visibly calms redness, and improves moisture retention — making skin feel less reactive and more resilient. Matriskin uses biomimetic formulations that pair Vitamin B3 with peptides, zinc, and barrier lipids for high performance with excellent tolerance.
How Niacinamide Works in the Skin
Niacinamide (nicotinamide) optimises multiple pathways at once: it supports ceramide synthesis for better moisture retention, helps regulate sebum, and moderates inflammation mediators linked to redness and sensitivity. Over time, skin looks clearer, smoother, and better balanced.
- Oil regulation: helps normalise sebum flow for a fresher, less-shiny look.
- Redness relief: soothes visible irritation and post-blemish unevenness.
- Barrier support: promotes ceramide production to reduce TEWL and tightness.
- Pore & texture refinement: with consistent use, improves the look of enlarged pores and roughness.
“Niacinamide is balance for the skin — clearer pores, calmer tone, stronger barrier.“
Biomimicry for Clearer, Calmer, More Resilient Skin
Matriskin pairs niacinamide with complementary actives to maximise results while keeping formulas gentle: zinc compounds for clarity, peptides for repair signalling, and barrier lipids + hyaluronic acid to lock in moisture. This biomimetic approach respects skin biology and delivers visible improvements with excellent daily tolerance.
IN ESSENCE
Niacinamide restores balance — regulating oil, easing redness, and strengthening the barrier for smoother, more composed skin.
Niacinamide — Research Highlights
- Oil & shine: normalises sebum for a more matte, refined look.
- Redness & sensitivity: moderates inflammatory mediators to visibly calm skin.
- Barrier strength: supports ceramide synthesis, reducing transepidermal water loss.
- Texture & pores: with steady use, skin appears smoother and pores less pronounced.
Who Benefits from Niacinamide
- Combination or oily skin with visible shine or enlarged pores.
- Reactive, redness-prone, or post-blemish uneven tone.
- Skin experiencing barrier weakness, tightness, or dehydration.
- Those introducing vitamin C or retinoids who want extra tolerance and balance.
How to Use Niacinamide
Use once or twice daily after cleansing. Niacinamide layers well with peptides, zinc, hyaluronic acid, and vitamin C. For oilier skin, pair with lightweight hydrators; for sensitive or post-procedure phases, follow with barrier lipids (ceramides, cholesterol, fatty acids) to seal hydration.
Matriskin Formulas with / pairing with Niacinamide
Contains: Niacinamide
Osmolight A+SPS Control Cleanser
A balancing gel cleanser with niacinamide, zinc, and calming agents to regulate oil, reduce redness, and preserve comfort. Leaves skin clean, fresh, and composed — never stripped.
Key Complex: Niacinamide + Zinc + Calming Actives.
Mechanism: Helps normalise sebum and soothe visible redness while supporting the barrier.
Clinical Notes:
- Users report reduced shine and redness within 10–14 days.
- Skin feels clean yet comfortable; no tight, stripped sensation.
Vitamin C 5 Serum
Antioxidant brightening serum that pairs seamlessly with niacinamide to improve radiance and even tone. Designed for high absorption and daily tolerance.
Key Synergy: Stabilised Vitamin C + Niacinamide-friendly pH.
Mechanism: Brightens and defends; niacinamide complements by calming redness and strengthening the barrier.
Clinical Notes:
- Skin luminosity increased by +33 % after 4 weeks
- Pigmentation irregularities reduced by up to 25 % in 28 days.
- Collagen synthesis stimulation confirmed through in-vitro fibroblast studies.
- 95 % of users reported a visibly brighter, more even complexion after daily use.
RL/3 Barrier Repair Cream
Lipid-rebuilding cream to seal hydration and comfort reactive skin. Complements niacinamide routines by reinforcing the barrier with ceramides, cholesterol, and fatty acids.
Clinical Notes:
- +34 % increase in skin hydration after 30 minutes (corneometry)
- Hydration maintained up to 24 hours after a single application.
- Elasticity +19 % and TEWL –22 % after 2 weeks.
- Users reported immediate comfort and reduced tightness from first use.
Niacinamide & Skin Balance — Frequently Asked Questions
Curious how niacinamide transforms oily, reactive, or uneven skin into a smoother, calmer complexion?
This FAQ explores Matriskin’s biomimetic Vitamin B3 formulations — how niacinamide helps regulate oil, ease redness, and reinforce the skin barrier while remaining gentle enough for daily use.
Niacinamide, or Vitamin B3, supports sebum regulation, barrier repair, and even tone. It helps reduce redness, refine pores, and improve hydration — leaving the skin clearer and more resilient.
Matriskin combines niacinamide with peptides, zinc, and biomimetic lipids to enhance performance and tolerance. This balanced formulation delivers visible results without dryness or irritation.
Yes. Niacinamide helps calm inflammation, reduce oil production, and fade residual redness or uneven pigmentation after breakouts. Consistent use improves clarity and skin comfort.
Absolutely. Niacinamide is one of the most well-tolerated actives. Matriskin’s formulas maintain a physiological pH and include soothing agents that make them ideal even for reactive skin.
Yes. Niacinamide pairs perfectly with Vitamin C, peptides, and hyaluronic acid. Together they brighten, hydrate, and strengthen the barrier — providing complete daily support for balanced, healthy skin.











